Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21380735 | 0.98 | SPHK1 (0.47) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL21615917 | 0.98 | SPHK1 (0.47) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL117023 | 0.83 | SPHK1 (0.45) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL10456044 | 0.83 | SPHK1 (0.45) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL16005247 | 0.81 | OPRM1 (0.50) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| Hydrochloric Acid SCHEMBL115349 | 0.81 | SPHK1 (0.44) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| Hydrochloric Acid SCHEMBL8461419 | 0.81 | SPHK1 (0.44) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| Hydrochloric Acid SCHEMBL5183108 | 0.81 | SPHK1 (0.44) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL10575768 | 0.79 | LMNA (0.44) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL9575723 | 0.79 | SPHK1 (0.50) | OPRM1SPHK1TP53LAP3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344576-B1 | CATIONIC PHOSPHATIDES AND GLYCERIDES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2002-02-05 | — | — | US | disclosed |