Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924408 | 0.81 | HRH3 (1.00) | HRH3CYP19A1HRH4TAAR1 | |
| SCHEMBL7468703 | 0.80 | HRH3 (0.73) | HRH3CYP19A1HRH4TAAR1 | |
| SCHEMBL7939173 | 0.70 | HRH3 (0.58) | HRH3CYP19A1 | |
| Bromide SCHEMBL7939566 | 0.69 | HRH3 (0.57) | HRH3CYP19A1 | |
| SCHEMBL7468695 | 0.68 | HRH3 (0.60) | HRH3CYP19A1 | |
| SCHEMBL7703563 | 0.67 | HRH3 (0.55) | HRH3CYP19A1 | |
| SCHEMBL7703567 | 0.67 | HRH3 (0.55) | HRH3CYP19A1HRH4 | |
| Hydrochloric Acid SCHEMBL7474426 | 0.66 | HRH3 (0.54) | HRH3CYP19A1 | |
| SCHEMBL7505800 | 0.66 | HRH3 (0.54) | HRH3CYP19A1 | |
| SCHEMBL4405648 | 0.65 | IDO1 (0.65) | HRH3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057223-A2 | COMPOUNDS AZEPANE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | claimed |