Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7939566 | 0.99 | HRH3 (0.57) | HRH3CYP19A1ALDH1A1CYP3A4GABRA1 | |
| SCHEMBL7704752 | 0.80 | DAO (0.40) | HRH3ALDH1A1CYP3A4GABRA1TSHR | |
| SCHEMBL7924408 | 0.74 | HRH3 (1.00) | HRH3CYP19A1CYP3A4MAPT | |
| SCHEMBL7468703 | 0.73 | HRH3 (0.73) | HRH3CYP19A1 | |
| SCHEMBL7505800 | 0.71 | HRH3 (0.54) | HRH3CYP19A1 | |
| SCHEMBL6669234 | 0.71 | GAA (0.48) | ALDH1A1TSHRTDP1 | |
| SCHEMBL31377271 | 0.71 | ALDH1A1 (0.58) | HRH3ALDH1A1CYP3A4GABRA1TSHR | |
| SCHEMBL10569744 | 0.70 | ALDH1A1 (0.51) | ALDH1A1CYP3A4KDM4EMAPT | |
| SCHEMBL3716431 | 0.70 | HTT (0.53) | ALDH1A1TSHRTDP1 | |
| SCHEMBL7703566 | 0.70 | HRH3 (0.68) | HRH3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |