Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TYMP | P19971 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341208 | 1.00 | TYMS (0.56) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL7703575 | 1.00 | TYMS (0.56) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL3341212 | 1.00 | TYMS (0.56) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL8326876 | 0.93 | LMNA (0.64) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL8326880 | 0.93 | LMNA (0.64) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL23517951 | 0.91 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL22983972 | 0.91 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL22983968 | 0.91 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL2460807 | 0.91 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL14064188 | 0.91 | TYMS (0.56) | TYMSTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342485-B1 | ANTITUMOR AGENTS WITH NUCLEIC ACIDS | GMEINER, WILLIAM H. | 2002-01-29 | — | — | US | disclosed |