Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TYMP | P19971 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703575 | 1.00 | TYMS (0.56) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL7703578 | 1.00 | TYMS (0.56) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL3341212 | 1.00 | TYMS (0.56) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL8326876 | 0.93 | LMNA (0.64) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL8326880 | 0.93 | LMNA (0.64) | TYMSLMNASMN1; SMN2TYMPHSP90AA1 | |
| SCHEMBL23517951 | 0.91 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL22983972 | 0.91 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL22983968 | 0.91 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL2460807 | 0.91 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL14064188 | 0.91 | TYMS (0.56) | TYMSTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137203-B1 | ETHYNYLATED HETERODINUCLEOSIDE PHOSPHATE ANALOGS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | SCHOTT HERBERT (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-20100151001-A1 | ETHYNYLATED HETERODINUCLEOSIDE PHOSPHATE ANALOGS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | EBERHARD KARLS UNIVERSITAT TUBINGEN (DE) | 2010-06-17 | — | — | US | disclosed |
| EP-2137203-A1 | ETHYNYLATED HETERODINUCLEOSIDE PHOSPHATE ANALOGS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | Eberhard Karls Universität Tübingen (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008125583-A1 | ETHYNYLATED HETERODINUCLEOSIDE PHOSPHATE ANALOGS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) | 2008-10-23 | — | — | WO | disclosed |
| US-5843917-A | 5-Fluorouracil derivatives | GLAXO WELLCOME INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0726904-A1 | 5-FLUOROURACIL DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012606-A1 | 5-FLUOROURACIL DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100151001-A1 | ETHYNYLATED HETERODINUCLEOSIDE PHOSPHATE ANALOGS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | ENTPD5, NUDT1, ENPP1 | TYMS 87/4885LMNA 2372/4885SMN1; SMN2 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.