Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.49 |
| ▸ | GRM5 | P41594 | 5/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8201190 | 0.91 | FFAR1 (0.52) | CHRM2CHRM1CHRM3CA12CA1 | |
| SCHEMBL19291472 | 0.83 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CA12CA1 | |
| SCHEMBL29745229 | 0.83 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CA12CA1 | |
| SCHEMBL23843579 | 0.81 | CHRM2 (0.57) | CHRM2CHRM1CHRM3CA12CA1 | |
| SCHEMBL6132140 | 0.80 | GRM5 (0.66) | CHRM2CHRM1CHRM3CA12CA1 | |
| SCHEMBL30707880 | 0.80 | GRM5 (0.66) | CHRM2CHRM1CHRM3CA12CA1 | |
| SCHEMBL2155272 | 0.79 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CA12CA1 | |
| SCHEMBL8617907 | 0.79 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CA12CA1 | |
| SCHEMBL6201292 | 0.79 | APP (0.55) | CHRM2CHRM1CA12CA1CA2 | |
| SCHEMBL16298669 | 0.78 | CHRM2 (0.55) | CHRM2CHRM1CHRM3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121459-A | Single pot process for producing (Z)-azabicyclo oxime ethers | WARNER-LAMBERT COMPANY (US) | 2000-09-19 | — | — | US | claimed |
| EP-0968212-B1 | METHOD OF MAKING (1S, 4R)-1-AZABICYCLO 2.2.1]HEPTAN-3-ONE AND (1R, 4S), 1-AZABICYCLO 2.2.1]HEPTAN-3-ONE | WARNER LAMBERT CO (US) | 2002-04-17 | — | — | EP | disclosed |
| US-6121306-A | Method of making (1S, 4R)-1-azabicyclo[2.2.1]heptan-3-one and (1R, 4S), 1-azabicyclo[2.2.1]heptan-3-one | WARNER-LAMBERT COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| US-6121459-A | Single pot process for producing (Z)-azabicyclo oxime ethers | WARNER-LAMBERT COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0968212-A1 | METHOD OF MAKING (1S, 4R)-1-AZABICYCLO 2.2.1]HEPTAN-3-ONE AND (1R, 4S), 1-AZABICYCLO 2.2.1]HEPTAN-3-ONE | WARNER-LAMBERT COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998032759-A1 | METHOD OF MAKING (1S, 4R)-1-AZABICYCLO[2.2.1]HEPTAN-3-ONE AND (1R, 4S), 1-AZABICYCLO[2.2.1]HEPTAN-3-ONE | WARNER LAMBERT COMPANY (US) | 1998-07-30 | — | — | WO | disclosed |