Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703789 | 0.91 | CHRM2 (0.54) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| SCHEMBL27393702 | 0.76 | CHRM2 (0.46) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| SCHEMBL2155272 | 0.76 | CHRM2 (0.56) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| SCHEMBL19291472 | 0.76 | CHRM2 (0.56) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| SCHEMBL29745229 | 0.76 | CHRM2 (0.56) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| SCHEMBL7884371 | 0.74 | FFAR1 (0.57) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| SCHEMBL23843579 | 0.74 | CHRM2 (0.57) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| SCHEMBL23350659 | 0.73 | CHRM2 (0.54) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| SCHEMBL8707382 | 0.73 | CHRM2 (0.48) | FFAR1CHRM2CHRM1CHRM3CA12 | |
| 1,3-Dimethoxybenzene SCHEMBL28200783 | 0.73 | LMNA (0.61) | MEN1KMT2ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121459-A | Single pot process for producing (Z)-azabicyclo oxime ethers | WARNER-LAMBERT COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| EP-1021446-A1 | SINGLE POT PROCESS FOR PRODUCING (Z)-AZABICYCLO OXIME ETHERS | WARNER-LAMBERT COMPANY (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998032758-A1 | SINGLE POT PROCESS FOR PRODUCING (Z)-AZABICYCLO OXIME ETHERS | WARNER-LAMBERT COMPANY (US) | 1998-07-30 | — | — | WO | disclosed |