Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597682 | 0.81 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAPOLBMEN1 | |
| SCHEMBL9377925 | 0.72 | GPR3 (1.00) | GPR3HDAC4HDAC7HDAC5KDM4E | |
| SCHEMBL27961797 | 0.71 | HDAC4 (0.41) | GPR3HDAC4HDAC7HDAC5KDM4E | |
| SCHEMBL23356616 | 0.71 | GPR3 (0.54) | GPR3KCNA3HDAC4HDAC7HDAC5 | |
| SCHEMBL9388058 | 0.68 | NOTUM (0.41) | HDAC4HDAC7HDAC5KDM4EALDH1A1 | |
| SCHEMBL28283765 | 0.67 | HDAC4 (0.43) | HDAC4HDAC7HDAC5KDM4EALDH1A1 | |
| SCHEMBL2989515 | 0.67 | HDAC4 (0.66) | HDAC4HDAC7HDAC5GAAMEN1 | |
| SCHEMBL31613807 | 0.67 | HDAC4 (0.66) | HDAC4HDAC7HDAC5GAAMEN1 | |
| SCHEMBL1888409 | 0.67 | FFAR1 (0.54) | ALDH1A1GAAMEN1KMT2AFFAR1 | |
| SCHEMBL19953652 | 0.67 | ACE (0.47) | HDAC4HDAC7HDAC5HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915851-B1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | NEDERLANDEN STAAT (NL) | 2002-03-20 | — | — | EP | disclosed |
| US-6030803-A | FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) | 2000-02-29 | — | — | US | disclosed |