Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206070 | 0.83 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5206081 | 0.83 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL21239539 | 0.75 | FPR2 (0.51) | ITGALFPR2 | |
| SCHEMBL7706514 | 0.74 | ITGAL (0.60) | ITGALITGB2ICAM1 | |
| SCHEMBL5239341 | 0.73 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5203942 | 0.73 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL6314324 | 0.72 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL6314317 | 0.72 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL5201254 | 0.71 | ITGAL (0.61) | ITGALITGB2ICAM1FPR2 | |
| SCHEMBL11722683 | 0.71 | ITGAL (0.49) | ITGALITGB2ICAM1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350763-B1 | AND IMMUNE CELL-MEDIATED DISEASES; SELECTIVELY ANTAGONIZE THE BINDING OF THE CAMS TO THE LEUKOINTEGRINS; | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-02-26 | — | — | US | disclosed |