Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MB | P02144 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390229 | 0.85 | GAA (0.31) | GAA | |
| SCHEMBL19982850 | 0.84 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2HSD17B10L3MBTL1GAA | |
| SCHEMBL11795207 | 0.74 | MEN1 (0.43) | PKMMEN1KMT2ATDP1RAB9A | |
| SCHEMBL19983058 | 0.73 | TDP1 (0.34) | LMNASMN1; SMN2HSD17B10L3MBTL1GAA | |
| SCHEMBL20429846 | 0.73 | EPHX2 (0.33) | LMNASMN1; SMN2HSD17B10L3MBTL1GAA | |
| SCHEMBL19669627 | 0.72 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2HSD17B10L3MBTL1GAA | |
| SCHEMBL8115837 | 0.71 | SMN1; SMN2 (0.35) | LMNASMN1; SMN2HSD17B10L3MBTL1GAA | |
| SCHEMBL5960697 | 0.69 | SMN1; SMN2 (0.34) | LMNASMN1; SMN2HSD17B10L3MBTL1GAA | |
| SCHEMBL3113073 | 0.68 | — | — | |
| SCHEMBL22312264 | 0.68 | TDP1 (0.33) | LMNASMN1; SMN2HSD17B10L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352839-B1 | PREPARING VIRGINIAMYCINS FROM AN ENGINEERED MICROORGANISMS, HAVING THE ABILITY TO PREVENT BIOSYNTHESIS OF THE PRECURSOR ANTIBIOTIC; THE MICROORGANISM IS CULTURED IN THE PRESENCE OF A SECOND PRECURSOR AND THE STREPTOGRAMIN ANALOG IS RECOVERED | AVENTIS PHARMA S.A. (FR) | 2002-03-05 | — | — | US | disclosed |
| EP-0460168-A1 | DIRECT POSITIVE EMULSIONS. | EASTMAN KODAK CO (US) | 1991-12-11 | — | — | EP | disclosed |