Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695367 | 0.81 | RXFP1 (0.38) | L3MBTL1GAAHTTPOLBKMT2A | |
| SCHEMBL10140100 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2MAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL18726609 | 0.79 | GAA (0.34) | GAAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL22048032 | 0.79 | MAPT (0.33) | SMN1; SMN2HSD17B10L3MBTL1GAAPKM | |
| SCHEMBL27644272 | 0.79 | L3MBTL1 (0.44) | SMN1; SMN2L3MBTL1GAAHTTMAPT | |
| SCHEMBL22019074 | 0.76 | NPC1 (0.38) | SMN1; SMN2L3MBTL1GAAHTTMAPT | |
| SCHEMBL22202094 | 0.76 | — | — | |
| SCHEMBL23871973 | 0.76 | TP53 (0.43) | SMN1; SMN2GAAHTTMAPTPOLB | |
| SCHEMBL20867336 | 0.75 | HDAC1 (0.36) | L3MBTL1POLBLMNABRD4NR1I2 | |
| SCHEMBL19512667 | 0.74 | NFKB1 (0.40) | GAAALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | ASIA VISION LIMITED (CN) | 2024-07-18 | — | — | US | disclosed |
| WO-2023064458-A1 | SELECTIVE JAK2 INHIBITORS AND METHODS OF USE | YALE UNIVERSITY (US) | 2023-04-20 | — | — | WO | disclosed |
| EP-3596069-B1 | KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | SCRIPPS RESEARCH INST (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |
| US-8901072-B2 | Glycopeptide and lipoglycopeptide antibiotics with improved solubility | THE MEDICINES COMPANY (US) | 2014-12-02 | — | — | US | disclosed |
| CN-102712649-A | Benzimidazole derivatives and pharmaceutical compositions and uses thereof | KBP BIOSCIENCES CO LTD | 2012-10-03 | — | — | CN | disclosed |
| US-20060009496-A1 | Method for preventing hemoprotein and heme-mediated lipid peroxidation | OATES JOHN A | 2006-01-12 | — | — | US | disclosed |
| WO-2006002073-A2 | METHOD FOR PREVENTING HEME-INDUCED LIPID PEROXIDATION | VANDERBILT UNIVERSITY (US) | 2006-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009496-A1 | Method for preventing hemoprotein and heme-mediated lipid peroxidation | HMOX1, HMOX2, GPX4 | SMN1; SMN2 4673/4885HSD17B10 203/4885L3MBTL1 2377/4885 |
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | BCL2, BCL2L2, BCL2L1 | SMN1; SMN2 2622/4885HSD17B10 2205/4885L3MBTL1 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.