Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MB | P02144 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20429846 | 0.81 | EPHX2 (0.33) | TDP1ALDH1A1HSD17B10GAAPKM | |
| SCHEMBL16312906 | 0.74 | — | — | |
| SCHEMBL7704328 | 0.73 | LMNA (0.36) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL19982850 | 0.73 | SMN1; SMN2 (0.33) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL19669627 | 0.70 | SMN1; SMN2 (0.37) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5960697 | 0.67 | SMN1; SMN2 (0.34) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL2756716 | 0.64 | TDP1 (0.39) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8115837 | 0.64 | SMN1; SMN2 (0.35) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL14539914 | 0.64 | HSD17B10 (0.32) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL19450903 | 0.64 | PTK2 (0.37) | TDP1ALDH1A1HSD17B10GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |