Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.52 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697620 | 0.88 | SMN1; SMN2 (0.49) | ENPP1CRHR1MAPTKDM4EALDH1A1 | |
| SCHEMBL7699156 | 0.87 | SQOR (0.47) | ENPP1CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL7696142 | 0.86 | CYP1A2 (0.45) | ENPP1CRHR1MAPTKDM4EALDH1A1 | |
| SCHEMBL7696145 | 0.79 | CRHR1 (0.48) | CRHR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7692125 | 0.78 | KDM4E (0.59) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL7694007 | 0.75 | MAPT (0.55) | CRHR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7691801 | 0.75 | HPGD (0.51) | CRHR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7692631 | 0.74 | HPGD (0.50) | CRHR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13757342 | 0.74 | KDM4E (0.50) | CRHR1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL22072873 | 0.73 | ABL1 (0.52) | ENPP1MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026713-A1 | ANTIPARASITIC COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-04 | — | — | WO | disclosed |