Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 9/20 | 0.43 |
| ▸ | GAA | P10253 | 9/20 | 0.43 |
| ▸ | SI | P14410 | 9/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799478 | 0.83 | MGAM (0.48) | MGAMGAASIMGAM2HDAC3 | |
| SCHEMBL2465013 | 0.73 | SLC6A2 (0.57) | MGAMGAASIMGAM2HDAC3 | |
| SCHEMBL89060 | 0.69 | FOLH1 (0.55) | GAAHDAC8KMT2AMAPTALDH1A1 | |
| Benzene SCHEMBL27083018 | 0.69 | FOLH1 (0.55) | GAAHDAC8KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7974299 | 0.68 | FOLH1 (0.53) | GAAKMT2AMAPTALDH1A1HTT | |
| Potassium SCHEMBL16531822 | 0.68 | FOLH1 (0.53) | GAAHDAC8KMT2AMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL16531812 | 0.68 | FOLH1 (0.53) | GAAHDAC8KMT2AMAPTALDH1A1 | |
| SCHEMBL11094883 | 0.68 | FOLH1 (0.53) | GAAHDAC8KMT2AMAPTALDH1A1 | |
| Phosphine SCHEMBL28264956 | 0.68 | FOLH1 (0.53) | GAAHDAC8KMT2AMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9940062 | 0.68 | FOLH1 (0.53) | GAAHDAC8KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046153-A2 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST | FINETECH LABORATORIES LTD. (IL) | 2002-06-13 | — | — | WO | claimed |
| WO-2002046153-A2 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST | FINETECH LABORATORIES LTD. (IL) | 2002-06-13 | — | — | WO | disclosed |