Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 11/20 | 0.48 |
| ▸ | GAA | P10253 | 11/20 | 0.48 |
| ▸ | SI | P14410 | 11/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 11/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704428 | 0.83 | MGAM (0.43) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL2465013 | 0.79 | SLC6A2 (0.57) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL8895798 | 0.73 | CYP2C19 (0.47) | GAAHDAC8KMT2AMAPT | |
| SCHEMBL2995918 | 0.72 | HTR2A (0.51) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL1226003 | 0.71 | KMT2A (0.49) | MGAMGAASIMGAM2GPR84 | |
| Hydrazine SCHEMBL27559974 | 0.70 | ALDH1A1 (0.72) | GPR84MEN1KMT2A | |
| SCHEMBL4089990 | 0.70 | CYP2C19 (0.45) | GAAHDAC8MEN1KMT2AMAPT | |
| SCHEMBL64182 | 0.70 | GPR84 (0.77) | GPR84MEN1KMT2A | |
| SCHEMBL9309358 | 0.70 | HTR2A (0.56) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL6283244 | 0.70 | GPR84 (0.59) | MGAMGAASIMGAM2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186300-A1 | Process for the preparation of zafirlukast | FINETECH LABORATORIES LTD. (IL) | 2004-09-23 | — | — | US | claimed |
| WO-2002046153-A2 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST | FINETECH LABORATORIES LTD. (IL) | 2002-06-13 | — | — | WO | claimed |
| US-20040186300-A1 | Process for the preparation of zafirlukast | FINETECH LABORATORIES LTD. (IL) | 2004-09-23 | — | — | US | disclosed |
| US-20040186300-A1 | Process for the preparation of zafirlukast | FINETECH LABORATORIES LTD. (IL) | 2004-09-23 | — | — | US | disclosed |
| WO-2002046153-A3 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST | FINETECH LAB LTD (IL) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002046153-A2 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST | FINETECH LABORATORIES LTD. (IL) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002046153-A2 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST | FINETECH LABORATORIES LTD. (IL) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186300-A1 | Process for the preparation of zafirlukast | LTC4S, LTB4R, CMA1 | MGAM 1819/4885GAA 1916/4885SI 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.