Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985367 | 0.82 | CYP19A1 (0.39) | CYP19A1VCPMAPK1MAPTPOLB | |
| SCHEMBL6987190 | 0.75 | ALDH1A1 (0.54) | CYP19A1MAPK1MAPTTP53LMNA | |
| SCHEMBL1878657 | 0.74 | CYP19A1 (0.55) | CYP19A1VCPMAPK1 | |
| SCHEMBL6991503 | 0.73 | CYP19A1 (0.39) | CYP19A1VCP | |
| SCHEMBL11510867 | 0.70 | MAPT (0.68) | MAPK1MAPTLMNAPOLB | |
| SCHEMBL6491542 | 0.69 | MAPT (0.50) | KCNN3MAPK1MAPTLMNA | |
| SCHEMBL11080258 | 0.69 | MAPT (0.52) | MAPK1MAPTLMNA | |
| SCHEMBL6989729 | 0.68 | ROCK1 (0.53) | MAPTTP53LMNA | |
| SCHEMBL7232939 | 0.67 | EPHX2 (0.61) | MAPK1MAPT | |
| SCHEMBL15497176 | 0.67 | MEN1 (0.64) | MAPK1MAPTTP53LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |