Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28112857 | 0.95 | HTT (0.32) | L3MBTL1POLBHTTALDH1A1 | |
| SCHEMBL28113438 | 0.95 | HTT (0.32) | L3MBTL1POLBHTTALDH1A1 | |
| SCHEMBL28112847 | 0.81 | CYP1A2 (0.31) | — | |
| SCHEMBL27993431 | 0.81 | HTT (0.37) | L3MBTL1POLBHTTDPP4 | |
| SCHEMBL29286313 | 0.81 | HTT (0.37) | L3MBTL1POLBHTTDPP4 | |
| SCHEMBL28068309 | 0.81 | HTT (0.37) | L3MBTL1POLBHTTDPP4 | |
| SCHEMBL18952939 | 0.81 | L3MBTL1 (0.34) | L3MBTL1POLBCHRNB2CHRNA4CHRNA5 | |
| SCHEMBL3952875 | 0.79 | HTT (0.35) | L3MBTL1POLBHTTCHRNB2CHRNA4 | |
| SCHEMBL3956320 | 0.79 | HTT (0.35) | L3MBTL1POLBHTTCHRNB2CHRNA4 | |
| SCHEMBL7704576 | 0.79 | MAPT (0.38) | ALDH1A1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188027-A | Heteroaromatic analog derivative and the application in medicine thereof | 广东东阳光药业有限公司 | 2016-12-07 | — | — | CN | disclosed |