Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992299 | 0.87 | CACNA1B (0.42) | CACNA1BGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7707552 | 0.75 | LTB4R (0.31) | CACNA1BL3MBTL1 | |
| SCHEMBL7243695 | 0.73 | EPHX2 (0.51) | CACNA1BALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL6986838 | 0.70 | CNR2 (0.45) | KDM4EMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL7236890 | 0.69 | CACNA1B (0.39) | CACNA1BGAAMEN1ALDH1A1MAPT | |
| SCHEMBL7630588 | 0.69 | TSHR (0.42) | CACNA1BGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL6989533 | 0.69 | PDE9A (0.42) | CACNA1BGAAMEN1ALDH1A1KMT2A | |
| SCHEMBL92863 | 0.68 | CYP19A1 (0.43) | GAAMEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL14021628 | 0.68 | GAA (0.45) | GAA | |
| SCHEMBL769069 | 0.66 | MAPT (0.59) | GAAKDM4EMEN1ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |