Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992299 | 0.87 | CACNA1B (0.42) | CACNA1BATML3MBTL1 | |
| SCHEMBL7092382 | 0.86 | ITK (0.31) | ITK | |
| SCHEMBL7704580 | 0.75 | CACNA1B (0.41) | CACNA1BL3MBTL1 | |
| SCHEMBL7232820 | 0.74 | ALDH1A1 (0.39) | CYP1A2 | |
| SCHEMBL6986838 | 0.72 | CNR2 (0.45) | CNR2 | |
| SCHEMBL7237712 | 0.71 | RAD52 (0.36) | CYP1A2 | |
| SCHEMBL7630028 | 0.71 | ABCB1 (0.36) | L3MBTL1CYP1A2 | |
| SCHEMBL6987924 | 0.70 | PDE9A (0.37) | CACNA1BCYP1A2 | |
| SCHEMBL9171948 | 0.68 | TSHR (0.40) | — | |
| SCHEMBL9040496 | 0.67 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |