Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11454635 | 0.97 | CACNA2D1 (0.46) | — | |
| Bicarbonate SCHEMBL25298921 | 0.90 | CACNA2D1 (0.50) | — | |
| Bicarbonate SCHEMBL943135 | 0.90 | — | — | |
| Oxalic Acid SCHEMBL20162291 | 0.87 | CACNA2D1 (0.48) | — | |
| Carbamic Acid SCHEMBL28649188 | 0.87 | — | — | |
| Acetic Acid SCHEMBL6150069 | 0.84 | ALDH1A1 (0.62) | — | |
| Acetic Acid SCHEMBL8817349 | 0.84 | — | — | |
| Acetic Acid SCHEMBL2678979 | 0.84 | — | — | |
| Acetic Acid SCHEMBL21227 | 0.84 | ALDH1A1 (0.62) | — | |
| Acetic Acid SCHEMBL12474237 | 0.84 | ALDH1A1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322527-A1 | METHOD FOR PREPARING BIOSOURCED IONIC LIQUIDS FOR CATALYSIS | Université de Bourgogne (FR) | 2018-05-23 | — | — | EP | disclosed |
| CN-1244575-C | Sulfonylalkylamido hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1204144-C | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2005-06-01 | — | — | CN | disclosed |
| CN-1178954-C | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | G��D��ɪ����˾ | 2004-12-08 | — | — | CN | disclosed |
| US-6361940-B1 | IMMOBILIZATION; GENETIC ENGINEERING | QIAGEN GENOMICS, INC. | 2002-03-26 | — | — | US | disclosed |
| CN-1196732-A | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-10-21 | — | — | CN | disclosed |
| CN-1186499-A | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-07-01 | — | — | CN | disclosed |
| CN-1183767-A | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-06-03 | — | — | CN | disclosed |
| CN-1183102-A | Heterocyclic carbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-05-27 | — | — | CN | disclosed |
| EP-0025489-B1 | VINYLOGOUS CARBOXAMIDES, MEDICAMENTS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1983-07-20 | — | — | EP | disclosed |
| US-4288437-A | ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1981-09-08 | — | — | US | disclosed |
| EP-0025489-A1 | Vinylogous carboxamides, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1981-03-25 | — | — | EP | disclosed |