Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.48 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL943135 | 0.90 | — | — | |
| Bicarbonate SCHEMBL25298921 | 0.90 | CACNA2D1 (0.50) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| Carbamic Acid SCHEMBL28649188 | 0.87 | — | — | |
| Acetic Acid SCHEMBL7704585 | 0.87 | — | — | |
| Oxalic Acid SCHEMBL11468911 | 0.84 | GABRR1 (0.43) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| Acetic Acid SCHEMBL11454635 | 0.84 | CACNA2D1 (0.46) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| Succinic Acid SCHEMBL28474785 | 0.81 | LMNA (0.53) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| Oxalic Acid SCHEMBL10743890 | 0.81 | ALDH1A1 (0.59) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| Cadaverine Tartrate SCHEMBL27481782 | 0.79 | TSHR (0.56) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| Methyl Alcohol SCHEMBL27870275 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322527-A1 | METHOD FOR PREPARING BIOSOURCED IONIC LIQUIDS FOR CATALYSIS | Université de Bourgogne (FR) | 2018-05-23 | — | — | EP | disclosed |
| CN-1244575-C | Sulfonylalkylamido hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1204144-C | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2005-06-01 | — | — | CN | disclosed |
| CN-1178954-C | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | G��D��ɪ����˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1196732-A | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-10-21 | — | — | CN | disclosed |
| CN-1186499-A | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-07-01 | — | — | CN | disclosed |
| CN-1183767-A | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-06-03 | — | — | CN | disclosed |
| CN-1183102-A | Heterocyclic carbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-05-27 | — | — | CN | disclosed |