Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701276 | 0.83 | — | — | |
| SCHEMBL7701907 | 0.76 | TSHR (0.31) | — | |
| SCHEMBL7696998 | 0.72 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL6448246 | 0.72 | SMN1; SMN2 (0.42) | CYP4F2CYP4A11 | |
| SCHEMBL20437994 | 0.70 | TDP1 (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL20438002 | 0.70 | TDP1 (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL20438000 | 0.70 | TDP1 (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL15297874 | 0.70 | TDP1 (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL30750429 | 0.70 | SMN1; SMN2 (0.32) | CYP4F2CYP4A11 | |
| SCHEMBL6260578 | 0.68 | CYP4F2 (0.39) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056716-B1 | CYCLOHEXANEDIOLE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| US-6184422-B1 | TREATMENT AND PREVENTION OF HYPERPROLIFERATIVE SKIN DISEASES; REVERSING CONDITIONS ASSOCIATED WITH PHOTODAMAGE; ANTITUMOR, -CARCINOGENIC AGENTS; PSORIASIS; DISORDERS OF NEOPLASTIC DISEASES; KERATINIZATION/KERATOSIS; ACNE; SEBORRHEA | HOFFMAN-LA ROCHE INC. | 2001-02-06 | — | — | US | disclosed |
| EP-1056716-A1 | CYCLOHEXANEDIOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043646-A1 | CYCLOHEXANEDIOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-02 | — | — | WO | disclosed |