Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.60 |
| ▸ | ELOVL6 | Q9H5J4 | 14/20 | 0.57 |
| ▸ | PGR | P06401 | 4/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041683 | 0.88 | ELOVL6 (0.58) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| SCHEMBL3034041 | 0.85 | ELOVL6 (0.60) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| SCHEMBL3036325 | 0.85 | ELOVL6 (0.58) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| SCHEMBL3032379 | 0.84 | ELOVL6 (0.57) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| SCHEMBL7650332 | 0.82 | CYP46A1 (0.47) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| SCHEMBL3037679 | 0.82 | ELOVL6 (0.62) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| SCHEMBL8087172 | 0.82 | ELOVL6 (0.54) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| SCHEMBL3037732 | 0.82 | ELOVL6 (0.60) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| SCHEMBL13908047 | 0.82 | ELOVL6 (0.60) | CYP46A1ELOVL6PGRNR3C1NR1I2 | |
| Hydrochloric Acid SCHEMBL3033669 | 0.81 | ELOVL6 (0.58) | CYP46A1ELOVL6PGRNR3C1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348616-B1 | CHEMICAL INTERMEDIATES FOR SYNTHESIS OF DESIRED BENZOXAZINONES | PIERCE MICHAEL ERNEST (US) | 2002-02-19 | — | — | US | disclosed |
| US-6147210-A | Practical synthesis of benzoxazinones useful as HIV reverse transcriptase inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-14 | — | — | US | disclosed |