Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL6 | Q9H5J4 | 15/20 | 0.54 |
| ▸ | CYP46A1 | Q9Y6A2 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030760 | 0.88 | ELOVL6 (0.59) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3034041 | 0.84 | ELOVL6 (0.60) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3036325 | 0.84 | ELOVL6 (0.58) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3041683 | 0.82 | ELOVL6 (0.58) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL7704788 | 0.82 | CYP46A1 (0.60) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3037679 | 0.81 | ELOVL6 (0.62) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL13908047 | 0.81 | ELOVL6 (0.60) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3037732 | 0.81 | ELOVL6 (0.60) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| Hydrochloric Acid SCHEMBL3033669 | 0.80 | ELOVL6 (0.58) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3032379 | 0.78 | ELOVL6 (0.57) | ELOVL6CYP46A1PGRNR1I2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582455-B1 | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO INC (US) | 2000-11-02 | — | — | EP | disclosed |
| US-5811423-A | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO., INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5665720-A | MIXTURE WITH NUCLEOSIDE ANALOG | MERCK & CO., INC. (US) | 1997-09-09 | — | — | US | disclosed |
| US-5663169-A | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO., INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5519021-A | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO., INC. (US) | 1996-05-21 | — | — | US | disclosed |
| WO-1995020389-A1 | BENZOXAZINONES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| WO-1994003440-A1 | BENZOXAZINONES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| EP-0582455-A1 | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1994-02-09 | — | — | EP | disclosed |