Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | USP14 | P54578 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092292 | 0.79 | CYP2C19 (0.36) | TSHRNFKB1CYP2C19USP14 | |
| SCHEMBL24577937 | 0.71 | TSHR (0.33) | TSHRNFKB1CYP2C19 | |
| SCHEMBL2058181 | 0.70 | — | — | |
| SCHEMBL21865016 | 0.70 | BDKRB2 (0.34) | TSHRNFKB1CYP2C19USP14 | |
| SCHEMBL4088584 | 0.69 | KDM4E (0.43) | TSHR | |
| SCHEMBL24577996 | 0.68 | TSHR (0.36) | TSHRNFKB1CYP2C19USP14 | |
| SCHEMBL9281240 | 0.67 | — | — | |
| SCHEMBL3381209 | 0.67 | — | — | |
| SCHEMBL9286272 | 0.65 | PARP1 (0.33) | — | |
| SCHEMBL18969620 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353044-B1 | PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2002-03-05 | — | — | US | disclosed |