Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708269 | 0.98 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2GALR2MITF | |
| SCHEMBL6999500 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2GALR2MITF | |
| SCHEMBL6995241 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2GALR2MITF | |
| SCHEMBL6993182 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2GALR2MITF | |
| SCHEMBL6994446 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2GALR2MITF | |
| SCHEMBL6994344 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2GALR2MITF | |
| SCHEMBL6996661 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2GALR2MITF | |
| SCHEMBL7704925 | 0.78 | MEN1 (0.40) | ALDH1A1POLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL10679958 | 0.76 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2POLBNPC1 | |
| SCHEMBL7713466 | 0.75 | MEN1 (0.40) | ALDH1A1LMNAPOLBHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |