Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237194 | 1.00 | KMT2A (0.51) | KMT2APOLBTDP1FABP5FABP7 | |
| SCHEMBL3427659 | 1.00 | KMT2A (0.51) | KMT2APOLBTDP1FABP5FABP7 | |
| SCHEMBL2116826 | 0.99 | KMT2A (0.49) | KMT2APOLBTDP1FABP5FABP7 | |
| SCHEMBL16598273 | 0.95 | KMT2A (0.47) | KMT2APOLBTDP1FABP5FABP7 | |
| SCHEMBL6426462 | 0.90 | KMT2A (0.47) | KMT2AFABP5FABP7TNFCA1 | |
| SCHEMBL8332721 | 0.90 | KMT2A (0.47) | KMT2AFABP5FABP7TNFCA1 | |
| SCHEMBL17110562 | 0.88 | KMT2A (0.50) | KMT2AFABP5FABP7TNFTLR2 | |
| SCHEMBL16678782 | 0.86 | KMT2A (0.48) | KMT2AFABP5FABP7TLR2CA1 | |
| SCHEMBL14759878 | 0.85 | KMT2A (0.60) | KMT2AFABP5FABP7TNFCA1 | |
| SCHEMBL22095619 | 0.85 | KMT2A (0.47) | KMT2APOLBTDP1FABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1379786-A | Modified peptides and peptidomimetics for use in immunotherapy | AKZO NOBEL NV (NL) | 2002-11-13 | — | — | CN | disclosed |
| EP-1226167-A1 | MODIFIED PEPTIDES AND PEPTIDOMIMETICS FOR USE IN IMMUNOTHERAPY | Akzo Nobel N.V. (NL) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001029081-A1 | MODIFIED PEPTIDES AND PEPTIDOMIMETICS FOR USE IN IMMUNOTHERAPY | AKZO NOBEL N.V. (NL) | 2001-04-26 | — | — | WO | disclosed |
| WO-1994029333-A1 | IMMUNOREACTIVE REAGENTS EMPLOYING MONOAMINE OXIDASE | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |