SCHEMBL2116826

SCHEMBL2116826

NC(CCCCC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
FABP5 Q01469 3/20 0.43
FABP7 O15540 2/20 0.43
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
EPHX2 P34913 1/20 0.39
TNF P01375 3/20 0.39
MDM4 O15151 1/20 0.39
TP53 P04637 1/20 0.39
CASP3 P42574 1/20 0.38
TLR2 O60603 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3427659 0.99 KMT2A (0.51) KMT2AFABP5FABP7POLBTDP1
SCHEMBL14237194 0.99 KMT2A (0.51) KMT2AFABP5FABP7POLBTDP1
SCHEMBL7705059 0.99 KMT2A (0.51) KMT2AFABP5FABP7POLBTDP1
SCHEMBL16598273 0.96 KMT2A (0.47) KMT2AFABP5FABP7POLBTDP1
SCHEMBL6426462 0.91 KMT2A (0.47) KMT2AFABP5FABP7CA1CA2
SCHEMBL8332721 0.91 KMT2A (0.47) KMT2AFABP5FABP7CA1CA2
SCHEMBL16678782 0.87 KMT2A (0.48) KMT2AFABP5FABP7CA1CA2
SCHEMBL17110562 0.86 KMT2A (0.50) KMT2AFABP5FABP7CA1CA2
SCHEMBL22095619 0.86 KMT2A (0.47) KMT2AFABP5FABP7POLBTDP1
SCHEMBL6369931 0.86 KMT2A (0.47) KMT2AFABP5FABP7POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516145-B2 Bioactive peptide brush polymers via photoinduced reversible-deactivation radical polymerization NORTHWESTERN UNIVERSITY (US) 2026-01-06 US disclosed
EP-4574166-A2 ANTIBODY-COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS JANSSEN Pharmaceutica NV (BE) 2025-06-25 EP disclosed
EP-3988123-B1 ANTIBODY-COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2025-02-26 EP disclosed
CN-118085061-A Cyclic peptide tyrosine compounds as neuropeptide y receptor modulators 詹森药业有限公司 2024-05-28 CN disclosed
CN-110099692-B Cyclic peptide tyrosine compounds as neuropeptide y receptor modulators 詹森药业有限公司 2024-03-12 CN disclosed
US-20240018208-A1 CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2024-01-18 US disclosed
US-20230365644-A1 ANTIBODY-COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2023-11-16 US disclosed
US-11767354-B2 Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors JANSSEN PHARMACEUTICA NV (BE) 2023-09-26 US disclosed
US-11732019-B2 Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors JANSSEN PHARMACEUTICA NV (BE) 2023-08-22 US disclosed
US-11591379-B2 Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors JANSSEN PHARMACEUTICA NV (BE) 2023-02-28 US disclosed
US-20100233743-A1 BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES UNIVERSITY OF TARTU (EE) 2010-09-16 US disclosed
EP-2057279-A2 BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES University of Tartu (EE) 2009-05-13 EP disclosed
WO-2008019696-A2 BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES UNIVERSITY OF TARTU (EE) 2008-02-21 WO disclosed
EP-0967205-B1 Labeling reactants and their use WALLAC OY (FI) 2003-09-17 EP disclosed
CN-1379786-A Modified peptides and peptidomimetics for use in immunotherapy AKZO NOBEL NV (NL) 2002-11-13 CN disclosed
EP-1226167-A1 MODIFIED PEPTIDES AND PEPTIDOMIMETICS FOR USE IN IMMUNOTHERAPY Akzo Nobel N.V. (NL) 2002-07-31 EP disclosed
WO-2001029081-A1 MODIFIED PEPTIDES AND PEPTIDOMIMETICS FOR USE IN IMMUNOTHERAPY AKZO NOBEL N.V. (NL) 2001-04-26 WO disclosed
EP-0967205-A1 Labeling reactants and their use WALLAC OY (FI) 1999-12-29 EP disclosed
EP-0710244-A1 IMMUNOREACTIVE REAGENTS EMPLOYING MONOAMINE OXIDASE THE WELLCOME FOUNDATION LIMITED (GB) 1996-05-08 EP disclosed
WO-1994029333-A1 IMMUNOREACTIVE REAGENTS EMPLOYING MONOAMINE OXIDASE THE WELLCOME FOUNDATION LIMITED (GB) 1994-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018208-A1 CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS NPY4R, NPY5R, NPY1R KMT2A 2517/4885FABP5 639/4885FABP7 867/4885
US-11732019-B2 Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors NPY4R, NPY5R, NPY1R KMT2A 2517/4885FABP5 639/4885FABP7 867/4885
US-11591379-B2 Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors NPY1R, NPY5R, NPY2R KMT2A 2481/4885FABP5 2236/4885FABP7 2292/4885
US-20230365644-A1 ANTIBODY-COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS NPY1R, NPY5R, NPY2R KMT2A 2481/4885FABP5 2236/4885FABP7 2292/4885
US-11767354-B2 Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors NPY1R, NPY5R, NPY2R KMT2A 2481/4885FABP5 2236/4885FABP7 2292/4885
US-20100233743-A1 BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES ADK, PRKCH, DMPK KMT2A 2009/4885FABP5 3400/4885FABP7 3387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.