Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094394 | 0.88 | MGLL (0.33) | ESR2PGRALOX5CYP1A2NPC1 | |
| SCHEMBL29085643 | 0.78 | CYP19A1 (0.31) | — | |
| SCHEMBL812104 | 0.78 | CYP19A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7705066 | 0.74 | GAA (0.33) | HTR2BTMEM97SIGMAR1HTR1AHTR7 | |
| SCHEMBL1454121 | 0.74 | HTR2C (0.34) | HTR2BTMEM97SIGMAR1HTR1AALOX5 | |
| SCHEMBL1452154 | 0.74 | HTR2C (0.34) | HTR2BTMEM97SIGMAR1HTR1AHTR7 | |
| SCHEMBL1453031 | 0.73 | HTR2C (0.33) | HTR2BTMEM97SIGMAR1HTR1AALOX5 | |
| SCHEMBL4652087 | 0.73 | L3MBTL1 (0.32) | HTR2BTMEM97SIGMAR1HTR1AALOX5 | |
| SCHEMBL1454234 | 0.73 | GAA (0.37) | HTR2BTMEM97SIGMAR1HTR1AHTR7 | |
| SCHEMBL8382207 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37573-E1 | Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands | BASELL POLYOLEFIN GMBH (DE) | 2002-03-05 | — | — | US | disclosed |
| US-5455365-A | Metallocene compound containing substituted indenyl ligand and transition metal element from groups IVb, Vb, or VIb; addition polymerization with aluminoxane cocatalyst | HOECHST AG (DE) | 1995-10-03 | — | — | US | disclosed |