Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711204 | 0.81 | NPC1 (0.47) | MAPTNPC1RAB9AADRB2ADRB1 | |
| SCHEMBL28510951 | 0.76 | ALDH1A1 (0.47) | MAPTNPC1RAB9AADRB2ADRB1 | |
| SCHEMBL7713596 | 0.76 | NPC1 (0.51) | MAPTNPC1RAB9AADRB2ADRB1 | |
| SCHEMBL7705118 | 0.76 | MAPT (0.42) | MAPTNPC1RAB9AADRB2ADRB1 | |
| SCHEMBL7705113 | 0.76 | MAPT (0.42) | MAPTNPC1RAB9AADRB2ADRB1 | |
| SCHEMBL9592549 | 0.74 | TP53 (0.50) | NPC1SMN1; SMN2GPR119 | |
| SCHEMBL9592542 | 0.74 | TP53 (0.50) | NPC1SMN1; SMN2GPR119 | |
| SCHEMBL9591128 | 0.74 | TP53 (0.50) | NPC1SMN1; SMN2GPR119 | |
| SCHEMBL9591115 | 0.74 | TP53 (0.50) | NPC1SMN1; SMN2GPR119 | |
| SCHEMBL9592152 | 0.74 | TP53 (0.50) | NPC1SMN1; SMN2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358574-B1 | CROSSLINKED POLYSILOXANES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2002-03-19 | — | — | US | disclosed |