Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713596 | 0.85 | NPC1 (0.51) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL17460993 | 0.82 | NPC1 (0.49) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL9923605 | 0.82 | NPC1 (0.49) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL7705128 | 0.81 | MAPT (0.40) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL28510951 | 0.80 | ALDH1A1 (0.47) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL12926231 | 0.80 | MAPT (0.46) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL6931905 | 0.78 | ELANE (0.51) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL7259849 | 0.78 | ELANE (0.51) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL13289665 | 0.77 | POLB (0.43) | MAPTPOLBSTSAPEX1HTT | |
| SCHEMBL7775226 | 0.77 | ELANE (0.51) | NPC1MAPTRAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358574-B1 | CROSSLINKED POLYSILOXANES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2002-03-19 | — | — | US | disclosed |