Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584872 | 0.89 | CYP11B2 (0.52) | CYP1A2CYP2D6CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL2286074 | 0.86 | CYP1A2 (0.48) | CYP1A2CYP2D6CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6456118 | 0.82 | G6PC1 (0.49) | CYP1A2CYP2D6TDP1ALDH1A1 | |
| SCHEMBL8200491 | 0.81 | CYP11B2 (0.47) | CYP1A2CYP2D6CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL8202649 | 0.79 | CYP3A4 (0.48) | CYP1A2CYP2D6HRH1ALDH1A1 | |
| SCHEMBL7380489 | 0.78 | CYP1A2 (0.48) | CYP1A2CYP2D6CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6610357 | 0.78 | — | — | |
| SCHEMBL2208034 | 0.77 | CYP11B2 (0.57) | CYP1A2CYP2D6NAPRTALDH1A1LTA4H | |
| SCHEMBL5413629 | 0.77 | NPC1 (0.53) | CYP1A2CYP2D6CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7381239 | 0.76 | CACNA1H (0.45) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348477-B1 | SUBSTITUTED PHENYL THIAZOLE DERIVATIVES AS VIRICIDES | BOEHRINGER INGELHEIM(CANADA) LTD. (CA) | 2002-02-19 | — | — | US | claimed |
| CN-109563092-B | 2-phenylimidazo [4,5-B ] pyridin-7-amine derivatives useful as inhibitors of the activity of the mammalian tyrosine kinase ROR1 | 坎塞拉有限公司 | 2021-09-14 | — | — | CN | disclosed |