Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL923302 | 0.82 | MEN1 (0.53) | MEN1KMT2ATAAR1NPC1RAB9A | |
| SCHEMBL721007 | 0.81 | TAAR1 (0.56) | TAAR1NPC1RAB9APOLBPTGS1 | |
| SCHEMBL11660292 | 0.80 | PTGS1 (0.50) | MEN1KMT2ATAAR1NPC1RAB9A | |
| SCHEMBL21622793 | 0.80 | LMNA (0.61) | TAAR1POLBPTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL2030841 | 0.80 | TAAR1 (0.71) | TAAR1NPC1RAB9APOLBPTGS1 | |
| SCHEMBL28985382 | 0.79 | TAAR1 (0.54) | TAAR1NPC1RAB9APOLBPTGS1 | |
| SCHEMBL14433475 | 0.78 | LMNA (0.64) | MEN1KMT2ATAAR1NPC1RAB9A | |
| SCHEMBL2886837 | 0.78 | TAAR1 (0.52) | TAAR1PTGS1PTGS2TSHRCYP1A2 | |
| SCHEMBL28449371 | 0.77 | TAAR1 (0.50) | TAAR1NPC1RAB9APOLBPTGS1 | |
| SCHEMBL9864113 | 0.76 | PTGS1 (0.50) | TAAR1NPC1RAB9APOLBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020012403-A1 | AN IMPROVED PROCESS FOR DIASTER-EOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | Piramal Enterprises Limited (IN) | 2020-01-16 | — | — | WO | disclosed |
| CN-109134219-A | A method of synthesis benzil class derivative | 五邑大学 | 2019-01-04 | — | — | CN | disclosed |
| US-6355665-B1 | ANTIHISTAMINES, ANTIALLERGENS AND IRRITABLE BOWEL SYNDROME. | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-03-12 | — | — | US | disclosed |
| WO-1999005114-A2 | 1H-4(5)-SUBSTITUTED IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HISTAMINE H3 RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-02-04 | — | — | WO | disclosed |