SCHEMBL923302

SCHEMBL923302

Clc1ccc(Cc2cccs2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
POLB P06746 2/20 0.53
HPGD P15428 1/20 0.51
MAPT P10636 5/20 0.51
L3MBTL1 Q9Y468 4/20 0.50
NPC1 O15118 3/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.47
SLC6A3 Q01959 1/20 0.47
DRD4 P21917 1/20 0.46
DRD5 P21918 1/20 0.46
ABL1 P00519 1/20 0.46
LMNA P02545 3/20 0.45
ALDH1A1 P00352 3/20 0.45
RAB9A P51151 2/20 0.45
HTT P42858 2/20 0.45
KDM4E B2RXH2 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7705346 0.82 MEN1 (0.51) MEN1KMT2APOLBMAPTL3MBTL1
SCHEMBL45228 0.80 LMNA (0.50) POLBHPGDL3MBTL1NPC1SMN1; SMN2
SCHEMBL10953000 0.79 HPGD (0.46) MEN1KMT2APOLBHPGDLMNA
SCHEMBL3238290 0.79 LMNA (0.62) MEN1KMT2APOLBHPGDMAPT
SCHEMBL29337530 0.79 LTA4H (0.57) MEN1KMT2APOLBLMNATAAR1
SCHEMBL11660485 0.79 TAAR1 (0.42) MEN1KMT2AL3MBTL1LMNATAAR1
SCHEMBL7294757 0.79 CYP3A4 (0.52) MEN1KMT2APOLBHPGDL3MBTL1
SCHEMBL10525378 0.79 L3MBTL1 (0.55) MEN1KMT2AL3MBTL1DRD4LMNA
SCHEMBL20738474 0.79 MEN1 (0.61) MEN1KMT2APOLBHPGDMAPT
SCHEMBL3385419 0.79 MEN1 (0.54) MEN1KMT2APOLBHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118414003-A Perovskite solar cell, preparation method and corresponding electric equipment 宁德时代新能源科技股份有限公司 2024-07-30 CN claimed
EP-0719771-A1 Process for the preparation of methylene compounds and the compound 2-(2',4'-dichloro-5'-fluorobenzyl)-thiophene BAYER AG (DE) 1996-07-03 EP claimed
US-4661619-A TREATMENT OF AROMATIC MERCAPTAN WITH CARBON MONOXIDE AND WATER OR ALCOHOL AND COBALT CARBONYL CATALYST THE BRITISH PETROLEUM COMPANY P.L.C. (GB) 1987-04-28 US claimed
CN-118414003-A Perovskite solar cell, preparation method and corresponding electric equipment 宁德时代新能源科技股份有限公司 2024-07-30 CN disclosed
US-11970694-B2 Rapid display method in translational synthesis of peptide PEPTIDREAM INC. (JP) 2024-04-30 US disclosed
CN-111440207-B Cuprous complex, preparation method thereof and application thereof in synthesis of 3-indolyl thioether 上海应用技术大学 2023-08-29 CN disclosed
CN-114716296-A Efficient halogenation synthesis method of alkyl halide 北京大学 2022-07-08 CN disclosed
CN-114685331-A Process for producing 1, 2-dithioethane compound 华南理工大学 2022-07-01 CN disclosed
CN-114605377-A Disulfide compound, synthesis thereof and application thereof in preparation of pseudomonas aeruginosa quorum sensing inhibitor 浙江工业大学 2022-06-10 CN disclosed
CN-114213294-A Method for catalytically synthesizing disulfide compound by using basic zeolite molecular sieve 常州大学 2022-03-22 CN disclosed
CN-110809573-B Vinyl compound, ultraviolet absorber and resin composition 株式会社日本触媒 2022-03-08 CN disclosed
US-4752616-A Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use E. R. SQUIBB & SONS, INC. (US) 1988-06-21 US disclosed
EP-0146291-B1 PROCESS FOR THE PRODUCTION OF CARBOXYLIC ACIDS AND/OR ESTERS THEREOF The British Petroleum Company p.l.c. (GB) 1988-01-13 EP disclosed
US-4705802-A Omega-aryl-alkylthienyl-compounds and process for the treatment of chronically inflammatory processes in humans A. NATTERMANN & CIE GMBH (DE) 1987-11-10 US disclosed
US-4678804-A PHYTOPATHOGENS CHEVRON RESEARCH COMPANY (US) 1987-07-07 US disclosed
US-4661619-A TREATMENT OF AROMATIC MERCAPTAN WITH CARBON MONOXIDE AND WATER OR ALCOHOL AND COBALT CARBONYL CATALYST THE BRITISH PETROLEUM COMPANY P.L.C. (GB) 1987-04-28 US disclosed
EP-0155524-A1 -Omega-aryl-alkylthienyl compounds, process for their preparation and pharmaceutical products containing these compounds A. Nattermann & Cie. GmbH (DE) 1985-09-25 EP disclosed
EP-0146291-A1 Process for the production of carboxylic acids and/or esters thereof The British Petroleum Company p.l.c. (GB) 1985-06-26 EP disclosed
US-4123542-A FUNGICIDES, BACTERICIDES, ANTIPROTOZOAL AGENTS SYNTEX (U.S.A.) INC. (US) 1978-10-31 US disclosed
US-4055652-A 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof SYNTEX (U.S.A.) INC. (US) 1977-10-25 US disclosed