Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133280 | 0.78 | GSK3B (0.65) | GSK3BNPC1RAB9AATMKMT2A | |
| SCHEMBL5903882 | 0.78 | GSK3B (0.65) | GSK3BNPC1RAB9AATMKMT2A | |
| SCHEMBL6129997 | 0.77 | GSK3B (0.69) | GSK3BNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL15979696 | 0.75 | GSK3B (0.71) | GSK3BNPC1RAB9AATMKMT2A | |
| SCHEMBL5903874 | 0.72 | GSK3B (0.57) | GSK3BNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL10164982 | 0.72 | GSK3B (0.57) | GSK3BNPC1RAB9AATMALDH1A1 | |
| SCHEMBL6793998 | 0.72 | GSK3B (1.00) | GSK3BNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL5569894 | 0.72 | GSK3B (0.67) | GSK3BNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL8754605 | 0.70 | ERCC5 (0.57) | NPC1RAB9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9150313 | 0.70 | RAB9A (0.73) | GSK3BNPC1RAB9AATMALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588357-B1 | Isoxazoles derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5480857-A | Herbicidal 4-heteroaroylisoxazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | disclosed |