Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.57 |
| ▸ | F11 | P03951 | 7/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438351 | 1.00 | F2 (0.57) | F2F11PRSS1F10TMPRSS11D | |
| SCHEMBL6438356 | 1.00 | F2 (0.57) | F2F11PRSS1F10TMPRSS11D | |
| SCHEMBL6438710 | 0.94 | F2 (0.55) | F2F11PRSS1F10 | |
| SCHEMBL6438717 | 0.94 | F2 (0.55) | F2F11PRSS1F10 | |
| SCHEMBL3767038 | 0.94 | F11 (0.65) | F2F11PRSS1F10CYP3A4 | |
| SCHEMBL6438340 | 0.94 | F11 (0.65) | F2F11PRSS1F10CYP3A4 | |
| SCHEMBL6440387 | 0.92 | F11 (0.55) | F2F11PRSS1F10PKM | |
| SCHEMBL7955244 | 0.92 | F11 (0.55) | F2F11PRSS1F10PKM | |
| SCHEMBL6440392 | 0.92 | F11 (0.55) | F2F11PRSS1F10PKM | |
| Trifluoroacetic Acid SCHEMBL3765593 | 0.90 | F11 (0.63) | F2F11PRSS1F10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444672-B1 | ORAL BIOVAILABILITY; INHIBITORS OF THROMBIN AND/OR FACTOR XA; SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2002-09-03 | — | — | US | disclosed |