Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 9/20 | 0.55 |
| ▸ | F2 | P00734 | 9/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | F12 | P00748 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440392 | 1.00 | F11 (0.55) | F11F2PRSS1ALDH1A1PKM | |
| SCHEMBL6440387 | 1.00 | F11 (0.55) | F11F2PRSS1ALDH1A1PKM | |
| SCHEMBL6436848 | 0.94 | F11 (0.63) | F11F2PRSS1ALDH1A1PKM | |
| SCHEMBL6436846 | 0.94 | F11 (0.63) | F11F2PRSS1ALDH1A1PKM | |
| SCHEMBL6438356 | 0.92 | F2 (0.57) | F11F2PRSS1ALDH1A1PKM | |
| SCHEMBL7705487 | 0.92 | F2 (0.57) | F11F2PRSS1ALDH1A1PKM | |
| SCHEMBL6438351 | 0.92 | F2 (0.57) | F11F2PRSS1ALDH1A1PKM | |
| SCHEMBL6438710 | 0.91 | F2 (0.55) | F11F2PRSS1F10PRSS2 | |
| SCHEMBL6438717 | 0.91 | F2 (0.55) | F11F2PRSS1F10PRSS2 | |
| SCHEMBL6435295 | 0.90 | F11 (0.56) | F11F2PRSS1KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194409-B1 | SERINE PROTEASE INHIBITOR; BIOAVAILABILITY WHEN ADMINISTERED BY MOUTH | AKZO NOBEL N.V. (NL) | 2001-02-27 | — | — | US | disclosed |