Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.60 |
| ▸ | THRA | P10827 | 12/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708373 | 1.00 | THRB (0.60) | THRBTHRATSHRHPGDS1PR2 | |
| SCHEMBL9848685 | 0.90 | THRB (0.51) | THRBTHRATSHRHPGDHRH3 | |
| SCHEMBL7702677 | 0.84 | THRB (0.44) | THRBTHRATSHRHPGDS1PR2 | |
| SCHEMBL4647837 | 0.84 | THRB (0.59) | THRBTHRAMEN1KMT2A | |
| SCHEMBL4645645 | 0.84 | THRB (0.59) | THRBTHRAMEN1KMT2A | |
| SCHEMBL372258 | 0.83 | THRB (0.49) | THRBTHRATSHRHPGDHRH3 | |
| SCHEMBL7708379 | 0.82 | THRB (0.60) | THRBTHRATSHRS1PR2S1PR1 | |
| SCHEMBL7711136 | 0.82 | THRB (0.60) | THRBTHRATSHRS1PR2S1PR1 | |
| SCHEMBL7708426 | 0.81 | TSHR (0.47) | THRBTHRATSHRHPGDS1PR2 | |
| SCHEMBL447953 | 0.80 | THRB (0.51) | THRBTHRATSHRHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | claimed |