Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.44 |
| ▸ | THRA | P10827 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708426 | 0.97 | TSHR (0.47) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL6514876 | 0.85 | THRB (0.54) | THRBTHRATSHRHPGDALOX5 | |
| SCHEMBL7708373 | 0.84 | THRB (0.60) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL7705505 | 0.84 | THRB (0.60) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL7708479 | 0.84 | TSHR (0.49) | THRBTHRATSHRALDH1A1ALOX5 | |
| SCHEMBL10717185 | 0.83 | THRB (0.44) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL447953 | 0.82 | THRB (0.51) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL7067194 | 0.79 | THRA (0.50) | THRBTHRATSHRALDH1A1ALOX5 | |
| SCHEMBL7067841 | 0.79 | THRA (0.50) | THRBTHRATSHRALDH1A1ALOX5 | |
| SCHEMBL10605595 | 0.78 | TSHR (0.50) | THRBTHRATSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | claimed |