Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060624 | 0.80 | ELANE (0.64) | ELANEKDM1ACA2MAPTTDP1 | |
| SCHEMBL7705761 | 0.79 | CA12 (0.49) | ELANECA2TDP1LMNASMN1; SMN2 | |
| SCHEMBL4059798 | 0.79 | ELANE (0.72) | ELANEKDM1ANR1H2CA2MEN1 | |
| SCHEMBL7708791 | 0.78 | ELANE (0.50) | ELANEKDM1ANR1H2CA2MAPT | |
| SCHEMBL4061370 | 0.78 | ELANE (0.81) | ELANEKDM1ACA2MAPTTDP1 | |
| SCHEMBL7705585 | 0.77 | ELANE (0.60) | ELANEKDM1ANR1H2CA2MEN1 | |
| SCHEMBL3963461 | 0.77 | RIPK1 (0.39) | MEN1KMT2A | |
| SCHEMBL6607118 | 0.76 | CYP17A1 (0.49) | — | |
| SCHEMBL82142 | 0.76 | ELANE (0.67) | ELANEKDM1ACA2MAPTTDP1 | |
| SCHEMBL11771781 | 0.76 | ELANE (0.67) | ELANEKDM1ACA2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |