Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178788 | 0.81 | PTGER4 (0.50) | PTGER4PPARGAGTR1 | |
| SCHEMBL8556792 | 0.79 | ACSS2 (0.48) | ACSS2PPARGAGTR1 | |
| SCHEMBL1160137 | 0.72 | PPARG (0.53) | PPARGAGTR1 | |
| SCHEMBL1159886 | 0.71 | PPARG (0.56) | PPARGAGTR1 | |
| SCHEMBL1160063 | 0.71 | PPARG (0.50) | PTGER4PPARGAGTR1 | |
| SCHEMBL1159974 | 0.70 | PPARG (0.65) | PTGER4PPARGHDAC6HDAC1 | |
| SCHEMBL1179934 | 0.70 | PPARG (0.51) | PTGER4ACSS2PPARG | |
| SCHEMBL1160151 | 0.70 | PPARG (0.51) | ACSS2PPARG | |
| SCHEMBL1160263 | 0.69 | PTPN1 (0.47) | PPARGAGTR1 | |
| SCHEMBL1159998 | 0.69 | PPARG (0.48) | PPARGAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348032-B1 | POTENT COMPOUNDS THAT INDUCE APOPTOSIS IN NEOPLASTIC CELLS (BUT NOT SUBSTANTIALLY IN NORMAL CELLS), WITHOUT SUBSTANTIALLY INHIBITING PGE-2. | CELL PATHWAYS, INC. | 2002-02-19 | — | — | US | disclosed |