Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705642 | 0.79 | PTGER4 (0.46) | ACSS2AGTR1PPARG | |
| SCHEMBL6169026 | 0.74 | AGTR1 (0.51) | ACSS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6167804 | 0.73 | PPARG (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL7669594 | 0.72 | TP53 (0.54) | ACSS2MEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL6172717 | 0.71 | PPARG (0.53) | ACSS2PPARG | |
| SCHEMBL5317401 | 0.71 | HSD17B10 (0.73) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL6170399 | 0.71 | HSD17B10 (0.48) | ACSS2NPC1RAB9AGAAMAPT | |
| SCHEMBL6426492 | 0.71 | APAF1 (0.40) | ACSS2MEN1KMT2AMAPTHTT | |
| SCHEMBL3643686 | 0.70 | AGTR1 (0.53) | ACSS2MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6170063 | 0.70 | PPARG (0.54) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882718-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |