Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21144227 | 0.98 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL21377060 | 0.86 | ALDH1A1 (0.60) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL9528998 | 0.71 | SORT1 (0.59) | HSD17B10MTNR1B | |
| SCHEMBL1063939 | 0.68 | MAPT (0.52) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL22528851 | 0.66 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2ANPSR1KDM4E | |
| SCHEMBL22190355 | 0.61 | HSD17B10 (0.37) | ALDH1A1KMT2AMEN1MAPTHSD17B10 | |
| SCHEMBL9748643 | 0.61 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL29713365 | 0.61 | MAPT (0.45) | ALDH1A1KMT2AMEN1MAPTHSD17B10 | |
| SCHEMBL14489684 | 0.60 | MAPT (0.48) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL21210733 | 0.60 | MAPT (0.48) | ALDH1A1KMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079176-A1 | PROCESS FOR 2,4-DISUBSTITUTED-1,3,4-OXADIAZOLINE-5-THIONE AND 5-ONE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2002-10-10 | — | — | WO | disclosed |