Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.39 |
| ▸ | HTR3B | O95264 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062532 | 0.80 | BCHE (0.48) | HRH3KDM4EHTR3EHTR3BALDH1A1 | |
| SCHEMBL10893535 | 0.80 | MAPT (0.48) | HRH3MAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL8319386 | 0.79 | MAOB (0.65) | MAOBKDM4EALDH1A1TDP1NPC1 | |
| SCHEMBL1702814 | 0.76 | EGFR (0.45) | HRH3KMT2A | |
| SCHEMBL61467 | 0.71 | NPC1 (0.56) | KDM4EALDH1A1CYP1A2THPOTDP1 | |
| SCHEMBL11377536 | 0.69 | HRH3 (0.47) | HRH3KDM4EHTR3EHTR3BALDH1A1 | |
| SCHEMBL4041532 | 0.65 | NPY5R (0.47) | ALDH1A1TDP1MAPTHTTKDM1A | |
| SCHEMBL27829579 | 0.64 | CYP1A2 (0.70) | KDM4EALDH1A1CYP1A2TDP1NPC1 | |
| SCHEMBL125022 | 0.64 | MAPT (0.71) | MAOBKDM4EALDH1A1CYP1A2TDP1 | |
| SCHEMBL7004637 | 0.62 | NPC1 (0.47) | KDM4EALDH1A1CYP1A2THPOTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348290-B1 | Multilayer organic photoconductor including electrically conductive support having specific index of surface area | NIPPON INK AND CHEMICALS, INC. (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6017665-A | CHARGE GENERATION LAYER COATED ONTO A SUBSTRATE FROM A COATING SOLUTION CONTAINING BINDER, CHARGE GENERATING MATERIAL, AND AN ORGANOSILANE COMPOUND; ADHESION, DURABILITY | MITSUBISHI CHEMICAL AMERICA (US) | 2000-01-25 | — | — | US | disclosed |