SCHEMBL125022

SCHEMBL125022

CN(C)c1ccc(C2=NN(c3ccccc3)CC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.71
KDM4E B2RXH2 10/20 0.71
GLA P06280 5/20 0.71
MAPK1 P28482 3/20 0.71
TDP1 Q9NUW8 3/20 0.71
NPC1 O15118 3/20 0.71
RAB9A P51151 3/20 0.71
L3MBTL1 Q9Y468 2/20 0.71
MAOB P27338 2/20 0.70
ALDH1A1 P00352 9/20 0.45
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
GFER P55789 2/20 0.42
SMN1; SMN2 Q16637 6/20 0.41
ATM Q13315 3/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
HPGD P15428 5/20 0.41
LMNA P02545 4/20 0.41
S1PR2 O95136 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9778415 0.85 MAOB (0.51) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL8319386 0.84 MAOB (0.65) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL9778304 0.84 MAOB (0.50) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL157594 0.84 MAPT (1.00) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL9778252 0.82 MAOB (0.48) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL9778225 0.82 CYP2A6 (0.50) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL9778241 0.80 ALDH1A1 (0.48) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL11211211 0.80 KDM4E (0.77) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL12716578 0.80 MAPT (0.77) MAPTKDM4EGLAMAPK1TDP1
SCHEMBL8542902 0.79 RAB9A (0.71) MAPTKDM4EGLAMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 677 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6444385-B1 None US disclosed
US-20260140457-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-05-21 US disclosed
US-12624159-B2 Polyarylate resin and electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2026-05-12 US disclosed
EP-4354226-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-04-29 EP disclosed
US-20260110979-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2026-04-23 US disclosed
US-20260104655-A1 IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-04-16 US disclosed
US-20260099113-A1 ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE CANON KK (JP) 2026-04-09 US disclosed
US-20260099103-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-04-09 US disclosed
US-20260079414-A1 ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2026-03-19 US disclosed
US-20260064022-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-03-05 US disclosed
US-5004662-A Having increased sensitivity and mobility MITA INDUSTRIAL CO., LTD. (JP) 1991-04-02 US disclosed
US-4965155-A HIGH MOLECULAR WEIGHT POLYMERCONTAINING RHODANINE DERIVATIVE MITA INDUSTRIAL CO., LTD. (JP) 1990-10-23 US disclosed
EP-0390195-A1 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed
EP-0371791-A2 Electrophotographic photosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-06-06 EP disclosed
EP-0369765-A2 Electrophotographic photosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1990-05-23 EP disclosed
US-4925759-A Electrophotographic sensitive material with pyrrolopyrrole and benzidine derivatives MITA INDUSTRIAL CO., LTD. (JP) 1990-05-15 US disclosed
EP-0353067-A2 Electrophotographic photosensitive material containing m-phenylenediamine compound MITA INDUSTRIAL CO., LTD. (JP) 1990-01-31 EP disclosed
US-4877702-A PERYLENE TYPE ELECTRIC CHARGE GENERATING SUBSTANCE AND DIAMINE DERIVATIVE AS ELECTRIC CHARGE TRANSFERRING SUBSTANCE MITA INDUSTRIAL CO., LTD. (JP) 1989-10-31 US disclosed
EP-0318916-A2 Electrophotographic sensitive material MITA INDUSTRIAL CO. LTD. (JP) 1989-06-07 EP disclosed
EP-0314195-A2 Electrophotographic sensitive material MITA INDUSTRIAL CO. LTD. (JP) 1989-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260099103-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS NR2E3, ASIC3, GJB2 MAPT 1922/4885KDM4E 1250/4885GLA 4438/4885
US-20260104655-A1 IMAGE FORMING APPARATUS DSG1, MARK4, SMC4 MAPT 565/4885KDM4E 320/4885GLA 4454/4885
US-20260140457-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR CRY1, GJB2, ALDH1A2 MAPT 2167/4885KDM4E 1536/4885GLA 4676/4885
US-20260099113-A1 ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE GPER1, TGFBR1, KEAP1 MAPT 571/4885KDM4E 1229/4885GLA 2661/4885
US-12624159-B2 Polyarylate resin and electrophotographic photosensitive member REV1, RAD51, RER1 MAPT 3627/4885KDM4E 872/4885GLA 2254/4885
US-20260079414-A1 ELECTROPHOTOGRAPHIC APPARATUS CAD, CLTA, EPCAM MAPT 1142/4885KDM4E 2349/4885GLA 2006/4885
US-20260110979-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS POT1, TERB1, PSMA4 MAPT 567/4885KDM4E 844/4885GLA 506/4885
US-20260064022-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS NR2E3, DDT, ITGAL MAPT 2008/4885KDM4E 4100/4885GLA 3439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.