Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209791 | 0.81 | — | — | |
| SCHEMBL5353921 | 0.78 | MCL1 (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27976 | 0.78 | MGAM (0.61) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL4812141 | 0.76 | TSHR (0.54) | TSHRHSD17B10LMNAKDM4EKMT2A | |
| SCHEMBL15688315 | 0.75 | MGAM (0.58) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5573998 | 0.74 | — | — | |
| SCHEMBL11756126 | 0.73 | TSHR (0.61) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL570228 | 0.71 | — | — | |
| SCHEMBL53913 | 0.71 | — | — | |
| SCHEMBL3441102 | 0.71 | MGAM (0.69) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355713-B1 | THERMOPLASTIC RESINS ARE STABILIZED WITH B-ENAMINES OR DERIVATIVES OF ALCOHOLS,SUGARS, SUGAR ALCOHOLS, GLYCOSIDES AND OLIGOSACCHARIDES; DISCOLORATION INHIBITION | AKCROS, CHEMICALS (GB) | 2002-03-12 | — | — | US | disclosed |
| EP-0986605-A1 | BETA-KETOESTERS FOR USE AS POLYMER STABILISERS | AKCROS CHEMICALS (GB) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054246-A1 | β-KETOESTERS FOR USE AS POLYMER STABILISERS | AKCROS CHEMICALS (GB) | 1998-12-03 | — | — | WO | disclosed |
| EP-0881253-A1 | B-ketoesters for use as polymer stabilisers | AKCROS CHEMICALS (GB) | 1998-12-02 | — | — | EP | disclosed |