Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9932 | 0.81 | BACE1 (0.59) | ALDH1A1HSD17B10TSHRERN1MAPT | |
| SCHEMBL7441914 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TSHRERN1MAPT | |
| SCHEMBL396552 | 0.80 | TSHR (0.69) | ALDH1A1HSD17B10TSHRERN1MAPT | |
| SCHEMBL3683272 | 0.79 | TSHR (0.80) | ALDH1A1HSD17B10TSHRERN1MAPT | |
| SCHEMBL29617021 | 0.79 | TSHR (0.80) | ALDH1A1HSD17B10TSHRERN1MAPT | |
| Bicarbonate SCHEMBL27449726 | 0.79 | TSHR (0.67) | ALDH1A1HSD17B10TSHRERN1MAPT | |
| SCHEMBL4741066 | 0.78 | KMT2A (0.57) | ALDH1A1HSD17B10TSHRMAPTRAB9A | |
| SCHEMBL7642688 | 0.78 | TSHR (0.61) | ALDH1A1HSD17B10TSHRERN1MAPT | |
| SCHEMBL3230316 | 0.77 | TSHR (0.65) | ALDH1A1HSD17B10TSHRERN1MAPT | |
| SCHEMBL29500171 | 0.77 | TSHR (0.65) | ALDH1A1HSD17B10TSHRERN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |