SCHEMBL7705957

SCHEMBL7705957

CCCNNS(=O)(=O)C=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 3/20 0.39
ADH1A P07327 3/20 0.39
ADH7 P40394 3/20 0.39
CA1 P00915 2/20 0.39
PPARA Q07869 2/20 0.31
ADH1C P00326 2/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
EPHX1 P07099 1/20 0.30
ADH4 P08319 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4430993 0.72
SCHEMBL7205609 0.70
SCHEMBL29048051 0.64 PPARA (0.57) ADH1BADH1AADH7CA1PPARA
SCHEMBL106109 0.64
SCHEMBL308930 0.62
Dimethylamine SCHEMBL6813087 0.60 ADH1B (0.48) ADH1BADH1AADH7CA1ADH1C
Sulfuric Acid SCHEMBL15789313 0.60 PAOX (0.52) ADH1BADH1AADH7CA1PPARA
Sulfuric Acid SCHEMBL15789311 0.60 PAOX (0.52) ADH1BADH1AADH7CA1PPARA
Hydrochloric Acid SCHEMBL740345 0.59
SCHEMBL7713475 0.59 ADH1B (0.37) ADH1BADH1AADH7CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644188-B1 Process for the preparation of sulfur derivatives of imidazole and intermediates obtained AVENTIS PHARMA SA (FR) 2002-12-04 EP disclosed
EP-0644188-A1 Process for the preparation of sulfur derivatives of imidazole and intermediates obtained ROUSSEL UCLAF (FR) 1995-03-22 EP disclosed