Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374187 | 0.81 | LPL (0.30) | LPLLIPG | |
| SCHEMBL7860803 | 0.79 | TRPA1 (0.42) | TRPA1ALDH1A1TSHRLPLLIPG | |
| SCHEMBL3871815 | 0.79 | SNCA (0.40) | TRPA1ALDH1A1TSHRLPLLIPG | |
| SCHEMBL14986008 | 0.78 | TSHR (0.37) | TSHRLPLLIPG | |
| SCHEMBL14983354 | 0.75 | CYP2A6 (0.40) | ALDH1A1 | |
| SCHEMBL890386 | 0.74 | LPL (0.40) | LPLLIPG | |
| SCHEMBL4262348 | 0.74 | LPL (0.40) | LPLLIPG | |
| SCHEMBL14176040 | 0.72 | TRPA1 (0.36) | TRPA1ALDH1A1TSHRLPLLIPG | |
| SCHEMBL7709040 | 0.72 | LPL (0.40) | LPLLIPG | |
| SCHEMBL10019962 | 0.71 | LPL (0.35) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644188-B1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | AVENTIS PHARMA SA (FR) | 2002-12-04 | — | — | EP | claimed |
| EP-0644188-A1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | ROUSSEL UCLAF (FR) | 1995-03-22 | — | — | EP | claimed |
| CN-114195814-B | Hydroxy naphthalenone-phenylboronic acid compound, preparation method and application | 中国药科大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-114195814-A | Hydroxy naphthalenone-phenylboronic acid compound, preparation method and application | 中国药科大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-110156822-B | Naphthol-phenylboronic acid compound and preparation method and application thereof | 中国药科大学 | 2021-07-09 | — | — | CN | disclosed |
| EP-0644188-B1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | AVENTIS PHARMA SA (FR) | 2002-12-04 | — | — | EP | disclosed |
| US-5493046-A | A 1-((4-PHENYL)PHENYL)-METHYLENE)IMIDAZOLE | ROUSSEL-UCLAF (FR) | 1996-02-20 | — | — | US | disclosed |
| EP-0644188-A1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | ROUSSEL UCLAF (FR) | 1995-03-22 | — | — | EP | disclosed |
| US-5391732-A | Cardiotonic agents, hypotensive agents, antispasmodic agents | ROUSSEL-UCLAF (FR) | 1995-02-21 | — | — | US | disclosed |