Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435460 | 0.82 | NPC1 (0.31) | NPC1RAB9AALDH1A1 | |
| SCHEMBL20241461 | 0.78 | PNMT (0.41) | PNMTNPC1RAB9APGRKDM4E | |
| SCHEMBL32687413 | 0.78 | PNMT (0.41) | PNMTNPC1RAB9APGRKDM4E | |
| SCHEMBL8393409 | 0.77 | PNMT (0.38) | PNMTNPC1RAB9APGRACHE | |
| SCHEMBL5177272 | 0.76 | PNMT (0.40) | PNMTNPC1RAB9APGRKDM4E | |
| SCHEMBL5345640 | 0.76 | PGR (0.38) | PNMTNPC1RAB9APGRACHE | |
| SCHEMBL2043313 | 0.75 | PNMT (0.49) | PNMTNPC1RAB9APGRKDM4E | |
| Hydrochloric Acid SCHEMBL5345642 | 0.75 | PNMT (0.39) | PNMTNPC1RAB9APGRKDM4E | |
| Hydrochloric Acid SCHEMBL8393412 | 0.75 | PNMT (0.39) | PNMTNPC1RAB9APGRKDM4E | |
| Hydrochloric Acid SCHEMBL27407140 | 0.75 | NPC1 (0.41) | PNMTNPC1RAB9APGRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448349-B1 | STEREORIGID METALLOCENE FOR BLOCK GAS PHASE POLYMERIZING OLEFINS HAVING THREE OR MORE CARBON ATOMS | FINA RESEARCH, S.A. (BE) | 2002-09-10 | — | — | US | disclosed |
| EP-1049741-A2 | POLYOLEFINS AND USES THEREOF | FINA RESEARCH S.A. (BE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037711-A2 | POLYOLEFINS AND USES THEREOF | FINA RESEARCH S.A. (BE) | 1999-07-29 | — | — | WO | disclosed |